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There were 180 Bordetella infections; 116 (64%) were caused by B pertussis and 64 (36%) by B parapertussis.

Family doctors of each case were asked to identify healthy infants born consecutively after the case in each practice, to act as controls.Most systemic and local adverse events were significantly less common with aP vaccines than with wP vaccines for the primary series as well as for the booster dose. Also, consistent with the hypothesis that fetal cells contribute to ongoing maternal somatic maintenance, fetal cells have been identified in many healthy tissues in human mothers 10, 43, 44, 45 and rodent mothers 41, 42, 46, 47. Waning of vaccine-induced immunity has been cited as one of the reasons for the observed epidemiologic trend. Relative risk (RR) estimates were adjusted for site, receipt of another vaccine during pregnancy, and propensity to receive Tdap during pregnancy. Future studies will also need to consider the function of these cells, perhaps by flow sorting microchimeric cells (e.

Maternal hormones” such as oxytocin and prolactin are released in the brain and play important roles in “letdown” contractions in breastfeeding 73, maternal milk supply, as well as maternal calm and interest in the offspring 74. Neonatal complications including ventilation requirement, sepsis, intraventricular hemorrhage, and neonatal death were also similar. Gelet op het geringe en uitgesproken wisselend aantal gevallen dat jaarlijks in België wordt vastgesteld, is ervoor gekozen om genoemde ratio te berekenen op basis van de gecumuleerde maternale overlijdens en levendgeborenen van vijf opeenvolgende jaren, waarbij dan de daaruit berekende ratio op het middelste jaar geboekt wordt.An over‐reactive response from the maternal immune system to small numbers of fetal cells, or a comparable response to over‐proliferating fetal cells, may increase autoimmune disease susceptibility, or symptoms of an existing autoimmune disease.

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